Donna (Sissy) Marie Sise age, 68 passed away January 20, 2022 at South Fork Medical Center. Sissy was born in Knoxville, daughter of Calvin O. & Bonnie K. Sise, Sr. She was their youngest and only daughter. Sissy was a lifetime resident of the South Knoxville area. She loved her pets and all types of animals. She always surrounded herself with dogs, cats, horses, chickens, goats and any stray animal lucky enough to cross her path. Sissy is preceded in death by her parents Calvin O. & Bonnie K. Sise, Sr., brother Michael M. Sise, Sr. She is survived by her 3 brothers, Calvin (Patricia) Sise, Jr.; Franklin D. (Takeko) Sise, Sr.; Donald G. Sise and 2 sisters-in-law, Linda Sise, Donna Whaley Sise and 5 nieces, 5 nephews, 19 great nieces/nephews and 3 fur babies (Baby, Jasmine (Jaz) and Bell). The family will receive friends at Highland South Memorial Garden at a later date in February 2022.