She was a member of South Knoxville Church of God.
Shirley is preceded in death by her loving husband Virgil E. Sise and grandson Christopher Michael McDonald.
She is survived by her children Angelia E. (Ricky) Bedford, Pamela D. (David) Lawson and Mark (Donna) Sise; grandchildren Matthew Sise, Michael Sise and Emilee Bedford; great-grandchildren Keeley, Rileigh, Liam, Abigail, Aubrey, Cole, Knox and Elijah and great-great-grandson Nash.
The family welcome friends for a Graveside Service at Berry Highland South's Mausoleum on Thursday, August 24, 2023, at 11am.