Mary-Alice DeSpain

With deep sorrow, we announce that Mary-Alice DeSpain, age 78, of Missouri City, Texas, passed away on March 23, 2026. Mary-Alice was born on June 10, 1947, in Mineola, New York, to the late Alice and John Belo. In addition to being a loving wife, mother, grandmother, aunt, and friend, Mary-Alice was a devoted animal lover, avid gardener, and competitive card player.

Mary-Alice’s love language was gift-giving. While others might keep a gift shelf or drawer, she dedicated an entire room to collecting the perfect items for family and friends. Mary-Alice was always generously thinking of others.

Mary-Alice was preceded in death by her parents, Alice and John Belo; her infant sister, Mary Frances; and many aunts, uncles, and cousins from her big, beautiful Portuguese family. She is survived by her husband of fifty-seven years, Lawrence “Larry” DeSpain; daughter Michelle DeSpain; daughter and son-in-law Jennie and Freddy Donovan; grandchildren Cadence and Chloe Donovan; brother and sister-in-law John and Bonnie Belo; aunt Mary Lou Price; niece, Caroline Barton (Adam); and many beloved cousins.

A celebration of Mary-Alice’s life will take place on Monday, March 30, at 10 a.m. at The Settegast-Kopf Company at Sugar Creek, 15015 Southwest Freeway, Sugar Land, TX 77478. Friends and family are welcome to attend and share memories.

In lieu of flowers, please consider donating in Mary-Alice’s memory to the organization that rescued and fostered two of her precious fur babies, Blue and Eliza Jane: https://www.saverescue.org/donate