Xue-Han Ning

Occupation: physiologist, researcher

Born: Peng-Lai, Shandong, People's Republic of China, April 15, 1936

Passed Away: Seattle, Washington, United States of America, April 20, 2015

Education: MD, Shanghai 1st Medical College, People's Republic of China, 1960

Post grad., Chinese Traditional Medicine College for Advanced Study, 1960—1961

Postgrad. in Physiology, University Michigan, 1984—1987

Career: Research fellow, research associate, leader cardiovascular research group Shanghai Institute Physiology, Academy Sinica, 1960—1987, head, associate professor cardiovascular research unit, professor, chair hypoxia department, 1988-90, vice chairperson academic committee, 1988-90; National Institutes of Health international research fellow University Michigan, Ann Arbor, 1984-87; professor and director Key Lab of Hypoxia Physiology Academia Sinica, Shanghai, 1989-90

Career Related: Acting leader, High Altitude Physiology Group, Chinese mountaineering and sci. expedition team to Mount Everest, 1975; leader High Altitude Physiology Group, Department Metallurgical Industry of China and Ry. Engineering Corps, 1979; visiting professor department physiology Michigan State University, East Lansing, University Michigan, University Washington Medical School, 1989-97; affiliate professor, University Washington, 1997—; research scientist Children's Hospital and Regional Medical Center, Seattle, 1997—.

Creative Works: Author: High Altitude Physiology and Medicine, 1981, Reports on Scientific Expedition to Mount Qomolungma, High Altitude Physiology, 1980, Environment and Ecology of Qinghai-Xizang (Tibet) Plateau, 1982, Plateau Tin Road Health Line, 2006; member editorial board Chinese Journal Applied Physiology, 1984-1992, Acta Physiologica, 1988-90, Chinese Journal Physiology (Taiwan) 2004-; contributor articles to professional journals

Awards: Recipient Merit award Shanghai Sci. Congress, 1977, All-China Sci. Congress, Beijing, 1978, Super Class award Academia Sinica, Beijing, 1986, 1st Class award National Natural Scis., Beijing, 1987, 2d Class award Academy Sinica Sci. and Technological Achievements, Beijing, 1992, # 1 Best Article award Tzu-Chi Medical Journal, Taiwan, 1995, Shanghai 2006 Excellent Popular Sci. Reading award, 2007.

Achievements: Achievements include first electrocardiographly record at summit of Mount Everest; research in predictive evaluation of mountaineering performance; characteristics for high altitude adaptation and acclimatization; effect of medicinal herbs on cardiac performance; cardiovascular adaptation and resistance to hypoxia and ischemia; injury threshold of short-cycle-intermittent hypoxia and gene expression in heart; the critical temperature 30 degrees celsius "temperature protection threshold" for modulating myocardial energy, metabolic pathways, and gene expression to resist ischemia and hypoxia; the 29 degrees celsius "temperature injury threshold" for cardiac contractility in the beating heart in vivo; hypothermic cross adaptation protects heart from subsequent ischema and hypoxia by preserving signaling for mitochondrial biogenesis, activateing stress pathways and inactivating apoptosis to maintain myocardial stability and improve functional recovery during reperfusion and reoxygenation; the hypothermia protection has also been proved in human by treated with a hypothermia rescue (32 degrees C Central catheter then 33-35 degrees C for 24 hrs) after his own heart stopped more than 6 mins in 2009.

Memberships: Member Am. Physiological Society, Am. Heart Association, International Society Heart Research, Royal Society Medicine, International Society for Mountain Medicine.

Immigration: came to U.S., 1984

Family: Son of Yi-Xing and Liu Ning; Married Jian-Xin Fan, May 28, 1967.

Family History: Grandfather Xi-Quan was a doctor of traditional Chinese medicine and master of Si-Nai-Tang (the meaning is "seek truth from facts") Chinese Pharmacy. Father was the general manager of Li-Hua Textile Mill, Tsingdao, China, Wife, MD Shanghai First Medical College, 1960 an emeritus doctor and associate research professor in the Shanghai Research Institute of Sport Science. She was a medical and physiological researcher in the Research and Training Group of high jumper Zhu Jian-Hua, who broke the world record 3 times.

Arrangements under the direction of Acacia Memorial Park & Funeral Home, Seattle, Washington.