Margaret "Sis" A. Birmingham, nee Coyne, age 91, passed away peacefully surrounded by family on March 7, 2019. Loving wife of 49 years to the late Edward P. Birmingham, Sr.; Beloved mother to Edward P. (late Mary Beth) Birmingham, Jr., John (Dr. Audrey Bromberger) Birmingham, Michael (Nancy) Birmingham, the late Kathleen Birmingham, Mary Ellen Birmingham, Patricia Birmingham, and Maureen (Dan) Gunnell; Cherished grandma to Edward P. III, Kathleen (Aaron), Dan, Sean (Katie), Clare (Ian), Patrick, Ryan (Gina), Michael (Tatyanna), Mary Margaret, and Conor; Great-grandma to Reilly, Rosalie, Elizabeth, John, Brentley, and Brayden; Dear sister to twin James (Gerry), the late Mary (late William), and the late Catherine (late Patrick); Aunt, cousin, and friend to many. Funeral to begin 9:15 AM on Friday, 3/15, at Blake-Lamb Funeral Home, 4727 W 103rd, Oak Lawn, IL 60453 for a 10 AM Mass of Christian Burial at Queen of Martyrs Catholic Church, 10233 Central Park Ave, Evergreen Park, IL 60805. Interment Holy Sepulchre Cemetery. Visitation will be from 3-9 PM on Thursday, 3/14, at the Funeral Home. In lieu of flowers, donations may be made to Misericordia, Heart of Mercy, 6300 N Ridge, Chicago, IL 60660 or at www.misericordia.com using reference #1774A.