Arlene K. Agen (nee Zeisz) of Cheektowaga, NY. July 19, 2025. Beloved wife of 48 years to James; cherished mother of Chad (Katie), Brad (Katie) and the late Kelly; loving grandmother of Matthew, Emily, Luke, and Wyatt; dearest sister of Robin (Paul) Hochulski, Kent (Doreen) Zeisz, Suzette (John) Evans, Mark (Christine) Zeisz and the late Rose Marie Zeisz; adored daughter of the late John and Elizabeth Zeisz (nee Weber) and daughter-in-law of Pat Agen-Zybczynski, the late Dan Zybczynski and James Agen; survived by many nieces and nephews. Family will be present Wednesday 4-8 PM at HOY FUNERAL HOME, 3855 Seneca St., West Seneca. A Mass of Christian Burial will be held Thursday 10 AM at Fourteen Holy Helpers Church, 1345 Indian Church Rd., West Seneca. Please assemble at church. In lieu of flowers, memorials may be made to St. Jude Children’s Research Hospital.
